100% Marine Omega-3 contains EPA and DHA in fish gelatin softgels that are suitable for pescatarians and people with restricted diets. These softgels are bovine and porcine free. The easy-to-swallow softgels are 50% smaller than regular 1000 mg softgels, but with the same 300 mg dose of EPA/DHA. They are convenient for children aged six and older, as well as adolescents and adults with an aversion to large pills. EPA and DHA are important components of brain cells and help to support cognitive health and brain function (1,2,3,4,5). DHA is highly concentrated in the brain and retina, where it helps support the development of the brain, eyes and nerves in children up to 12 years of age (3,6,7). EPA and DHA also promote healthy levels of anti-inflammatory activity in the body (8,9). They play an important role to help maintain cardiovascular health and assist in lowering blood triglycerides/triacylglycerols levels (10,11,12). When used in combination with conventional therapy, they also help reduce the pain of rheumatoid arthritis in adults (13,14). Features and Benefits: Fish gelatin softgels that are suitable for pescatarians， Bovine and porcine free， Easy to swallow − 50% smaller size， Each softgel contains 180 mg of EPA and 120 mg of DHA， Clear-enteric softgels for reduced fishy aftertaste， Free of artificial colours, preservatives, and sweeteners， Contains no dairy, sugar, wheat, gluten, yeast, soy, corn, egg, shellfish, salt, tree nuts, or GMOs. NPN: 80032972， Dosage: Recommended dosage (children 6 years and older, adolescents & adults) : Take 3 clear enteric softgels daily or as directed by a physician. For triglyceride/triacylglycerol reduction (children 6 years and older, adolescents & adults) : Take 4 clear enteric softgels daily or as directed by a physician. For rheumatoid arthritis relief (adults) : Take 2 clear enteric softgels 5 times daily or as directed by a physician. For inflammation (adults) : Take 3 clear enteric softgels 2 times daily or as directed by a physician. Cautions or Warnings: Keep out of the reach of children， Storage: Store in airtight container, protected from light. For product freshness protect from heat and humidity， References: 1. Muldoon MF, Ryan CM, Yao JK, et al. Long-chain omega-3 fatty acids and optimization of cognitive performance. Mil Med. 2014;179:95-105. 2. Dyall SC. Long-chain omega-3 fatty acids and the brain: a review of the independent and shared effects of EPA, DPA and DHA. Front Aging Neurosci. 2015;7:52. 3. Chang CY, Ke DS, Chen JY. Essential fatty acids and human brain. Acta Neurol Taiwan. 2009;18:231-241. 4. Bo Y, Zhang X, Wang Y, et al. The n-3 polyunsaturated fatty acids supplementation improved cognitive function in the Chinese elderly with mild cognitive impairment: a double-blind randomized controlled trial. Nutrients. 2017;9(1):E54. 5. Chiu CC, Su KP, Cheng TC, et al. The effects of omega-3 fatty acids monotherapy in Alzheimer's disease and mild cognitive impairment: a preliminary randomized double-blind placebo-controlled study. Prog Neuropsychopharmacol Biol Psychiatry. 2008 Aug 1;32(6):1538-1544. 6. Portillo-Reyes V, Pérez-García M, Loya-Méndez Y, et al. Clinical significance of neuropsychological improvement after supplementation with omega-3 in 8-12 years old malnourished Mexican children: a randomized, double-blind, placebo and treatment clinical trial. Res Dev Disabil. 2014 Apr;35(4):861-870. 7. Harbild HL, Harsløf LB, Christensen JH, et al. Fish oil-supplementation from 9 to 12 months of age affects infant attention in a free-play test and is related to change in blood pressure. Prostaglandins Leukot Essent Fatty Acids. 2013;89:327-333. 8. Kiecolt-Glaser JK, Belury MA, Andridge R, et al. Omega-3 supplementation lowers inflammation in healthy middle-aged and older adults: a randomized controlled trial. Brain Behav Immun. 2012;26:988-995. 9. Kiecolt-Glaser JK, Belury MA, Andridge R, et al. Omega-3 supplementation lowers inflammation and anxiety in medical students: a randomized controlled trial. Brain Behav Immun. 2011;25:1725-1734. 10. Skulas-Ray AC, Kris-Etherton PM, Harris WS, et al. Dose-response effects of omega-3 fatty acids on triglycerides, inflammation, and endothelial function in healthy persons with moderate hypertriglyceridemia. Am J Clin Nutr. 2011;93:243-252. 11. Oh PC, Koh KK, Sakuma I, et al. Omega-3 fatty acid therapy dose-dependently and significantly decreased triglycerides and improved flow-mediated dilation, however, did not significantly improve insulin sensitivity in patients with hypertriglyceridemia. Int J Cardiol. 2014;176:696-702. 12. Koh KK, Quon MJ, Shin KC, et al. Significant differential effects of omega-3 fatty acids and fenofibrate in patients with hypertriglyceridemia. Atherosclerosis. 2012 Feb;220(2):537-544. 13. Miles EA, Calder PC. Influence of marine n-3 polyunsaturated fatty acids on immune function and a systematic review of their effects on clinical outcomes in rheumatoid arthritis. Br J Nutr. 2012; 107(Suppl 2):S171-S184. 14. Geusens P, Wouters C, Jiang, Y, et al. Long-term effect of omega-3 fatty acid supplementation in active rheumatoid arthritis. A 12-month, double-blind, controlled study. Arthritis Rheum. 1994 Jun;37(6):824-829.